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Article

Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides.

Frontiers in immunology - 1 Jan 2019

Mamedov Azad, Vorobyeva Nadezhda, Filimonova Ioanna, Zakharova Maria, Kiselev Ivan, Bashinskaya Vitalina, Baulina Natalia, Boyko Alexey, Favorov Alexander, Kulakova Olga, Ziganshin Rustam, Smirnov Ivan, Poroshina Alina, Shilovskiy Igor, Khaitov Musa, Sykulev Yuri, Favorova Olga, Vlassov Valentin, Gabibov Alexander, Belogurov Alexey

Abstract excerpt

Risk of the development of multiple sclerosis (MS) is known to be increased in individuals bearing distinct class II human leukocyte antigen (HLA) variants, whereas some of them may have a protective effect. Here we analyzed distribution of a highly polymorphous HLA-DRB1 locus in more than one thousand relapsing-remitting MS patients and healthy individuals of Russian ethnicity. Carriage of HLA-DRB1*15 and...

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Identifiers

PMID: 32010139
DOI: 10.3389/fimmu.2019.03088
PMCID: PMC6978714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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