Article
HLA-F transcriptional and protein differential expression according to its genetic polymorphisms.
HLA - 1 Nov 2023
Paganini Julien, Faux Pierre, Beley Sophie, Picard Christophe, Chiaroni Jacques, Di Cristofaro Julie
Abstract excerpt
Many specificities single out HLA-F: its structure, expression regulation at cell membrane and function. HLA-F mRNA is detected in the most cell types and the protein is localized in the ER and Golgi apparatus. When expressed at cell surface, HLA-F may be associated to β2-microglobulin and peptide or expressed as an open-conformer molecule. HLA-F reaches the membrane upon activation of different primary cell...
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