Article
Expression of classical HLA class I molecules: regulation and clinical impacts: Julia Bodmer Award Review 2015.
HLA - 1 May 2016
René C, Lozano C, Eliaou J-F
Abstract excerpt
Human leukocyte antigen (HLA) class I genes are ubiquitously expressed, but in a tissue specific-manner. Their expression is primarily regulated at the transcriptional level and can be modulated both positively and negatively by different stimuli. Advances in sequencing technologies led to the identification of new regulatory variants located in the untranslated regions (UTRs), which could influence the...
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