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Article

Language and spatial dysfunction in Alzheimer disease with white matter thorn-shaped astrocytes.

Neurology - 31 Mar 2020

Resende Elisa de Paula França, Nolan Amber L, Petersen Cathrine, Ehrenberg Alexander J, Spina Salvatore, Allen Isabel E, Rosen Howard J, Kramer Joel, Miller Bruce L, Seeley William W, Gorno-Tempini Maria Luiza, Miller Zachary, Grinberg Lea T

Abstract excerpt

OBJECTIVES: Alzheimer disease (AD) shows a broad array of clinical presentations, but the mechanisms underlying these phenotypic variants remain elusive. Aging-related astrogliopathy (ARTAG) is a relatively recent term encompassing a broad array of tau deposition in astroglia outside the range of traditional tauopathies. White matter thorn-shaped astrocyte (WM-TSA) clusters, a specific ARTAG subtype, has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32001514
DOI: 10.1212/WNL.0000000000008937
PMCID: PMC7274917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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