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Article

Mesial temporal astrocyte tau pathology in the MRC-CFAS ageing brain cohort.

Dementia and geriatric cognitive disorders - 1 Jan 2012

Lace G, Ince P G, Brayne C, Savva G M, Matthews F E, de Silva R, Simpson J E, Wharton S B

Abstract excerpt

BACKGROUND: Glial tau pathology is seen in certain tauopathies and in ageing. We determined its frequency in ageing mesial temporal lobe and its relationship to other tau pathologies in the MRC-CFAS population-representative neuropathology cohort. METHODS: Mesial temporal lobe, including hippocampus, amygdala, entorhinal cortex and white matter, was examined using immunohistochemistry with the AT8 antibody to...

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PMID: 22868294
DOI: 10.1159/000341581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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