Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical management and genomic profiling of pediatric low-grade gliomas in Saudi Arabia.

PloS one - 1 Jan 2020

Mobark Nahla A, Alharbi Musa, Alhabeeb Lamees, AlMubarak Latifa, Alaljelaify Rasha, AlSaeed Mariam, Almutairi Amal, Alqubaishi Fatmah, Ahmad Maqsood, Al-Banyan Ayman, Alotabi Fahad E, Barakeh Duna, AlZahrani Malak, Al-Khalidi Hisham, Ajlan Abdulrazag, Ramkissoon Lori A, Ramkissoon Shakti H, Abedalthagafi Malak

Abstract excerpt

Pediatric Low Grade Gliomas (PLGGs) display heterogeneity regarding morphology, genomic drivers and clinical outcomes. The treatment modality dictates the outcome and optimizing patient management can be challenging. In this study, we profiled a targeted panel of cancer-related genes in 37 Saudi Arabian patients with pLGGs to identify genetic abnormalities that can inform prognostic and therapeutic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Clinical Decision-Making

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Fusion

Share to Genomics

Share to Glioma

Share to High-Throughput Nucleotide Sequencing

Share to Saudi Arabia

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 31995621
DOI: 10.1371/journal.pone.0228356
PMCID: PMC6988947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical management and genomic profiling of pediatric low-grade gliomas in Saudi Arabia.PMID 31995621Read ↗

Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures.Semantic proximity Read ↗

Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas.Semantic proximity Read ↗

Genomic Profiling of a Large Set of Diverse Pediatric Cancers Identifies Known and Novel Mutations across Tumor Spectra.Semantic proximity Read ↗

Pediatric low-grade glioma in the era of molecular diagnostics.Semantic proximity Read ↗

Gliomas in children and adolescents: investigation of molecular alterations with a potential prognostic and therapeutic impact.Semantic proximity Read ↗

Clinical and Molecular Features of Disseminated Pediatric Low Grade Glioma - A Systematic Review of LiteratureSemantic proximity Read ↗

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas.Semantic proximity Read ↗

Cancer Predisposition Syndromes Associated With Pediatric High-Grade GliomasSemantic proximity Read ↗

Molecular alterations in the integrated diagnosis of pediatric glial and glioneuronal tumors: A single center experience.Semantic proximity Read ↗

High-Grade Gliomas and Cancer Predisposition Syndromes in children and adolescents: Unpacking the Impact through a Single-Center AnalysisSemantic proximity Read ↗

Pediatric low-grade gliomas can be molecularly stratified for risk.Semantic proximity Read ↗

Multiplex Detection of Pediatric Low-Grade Glioma Signature Fusion Transcripts and Duplications Using the NanoString nCounter System.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.