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Article

Multiplex Detection of Pediatric Low-Grade Glioma Signature Fusion Transcripts and Duplications Using the NanoString nCounter System.

Journal of neuropathology and experimental neurology - 1 Jul 2017

Ryall Scott, Arnoldo Anthony, Krishnatry Rahul, Mistry Matthew, Khor Kangzi, Sheth Javal, Ling Cino, Leung Stephie, Zapotocky Michal, Guerreiro Stucklin Ana, Lassaletta Alvaro, Shago Mary, Tabori Uri, Hawkins Cynthia E

Abstract excerpt

Previous studies identified recurrent fusion and duplication events in pediatric low-grade glioma (pLGG). In addition to their role in diagnosis, the presence of these events aid in dictating therapy and predicting patient survival. Clinically, BRAF alterations are most commonly identified using fluorescent in situ hybridization (FISH). However, this method is costly, labor-intensive and does not identify nonBRAF...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28863456
DOI: 10.1093/jnen/nlx042

Genes

BRAF
FGFR1
MYBL1
TACC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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