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Article

Genetic Risk of Coronary Artery Disease, Features of Atherosclerosis, and Coronary Plaque Burden.

Journal of the American Heart Association - 4 Feb 2020

Christiansen Morten Krogh, Nissen Louise, Winther Simon, Møller Peter Loof, Frost Lars, Johansen Jane Kirk, Jensen Henrik Kjærulf, Guðbjartsson Daníel, Holm Hilma, Stefánsson Kári, Bøtker Hans Erik, Bøttcher Morten, Nyegaard Mette

Abstract excerpt

Background Polygenic risk scores (PRSs) based on risk variants from genome-wide association studies predict coronary artery disease (CAD) risk. However, it is unknown whether the PRS is associated with specific CAD characteristics. Methods and Results We consecutively included 1645 patients with suspected stable CAD undergoing coronary computed tomography angiography. A multilocus PRS was calculated as the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31983321
DOI: 10.1161/JAHA.119.014795
PMCID: PMC7033858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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