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Article

A genome-wide association study of imaging-defined atherosclerosis

31 Mar 2025

Abstract excerpt

Imaging-defined atherosclerosis represents an intermediate phenotype of atherosclerotic cardiovascular disease (ASCVD). Genome-wide association studies (GWAS) on directly measured coronary plaques using coronary computed tomography angiography (CCTA) are scarce. In the so far largest population-based cohort with CCTA data, we performed a GWAS on coronary plaque burden as determined by the segment involvement...

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PMID: 40164586
DOI: 10.1038/s41467-025-57457-7

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