Article
Precision phenotyping, panomics, and system-level bioinformatics to delineate complex biologies of atherosclerosis: rationale and design of the "Genetic Loci and the Burden of Atherosclerotic Lesions" study.
Journal of cardiovascular computed tomography - 1 Jan 2000
Voros Szilard, Maurovich-Horvat Pal, Marvasty Idean B, Bansal Aruna T, Barnes Michael R, Vazquez Gustavo, Murray Sarah S, Voros Viktor, Merkely Bela, Brown Bradley O, Warnick G Russell
Abstract excerpt
BACKGROUND: Complex biological networks of atherosclerosis are largely unknown. OBJECTIVE: The main objective of the Genetic Loci and the Burden of Atherosclerotic Lesions study is to assemble comprehensive biological networks of atherosclerosis using advanced cardiovascular imaging for phenotyping, a panomic approach to identify underlying genomic, proteomic, metabolomic, and lipidomic underpinnings, analyzed by...
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