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Article

A common variant of LDL receptor related protein 2 (LRP2) gene is associated with gout susceptibility: a meta-analysis in a Japanese population.

Human cell - 1 Apr 2020

Akashi Airi, Nakayama Akiyoshi, Kamatani Yoichiro, Higashino Toshihide, Shimizu Seiko, Kawamura Yusuke, Imoto Misaki, Naito Mariko, Hishida Asahi, Kawaguchi Makoto, Takao Mikiya, Matsuo Michinori, Takada Tappei, Ichida Kimiyoshi, Ooyama Hiroshi, Shinomiya Nariyoshi, Matsuo Hirotaka

Abstract excerpt

Gout, which results from elevated serum uric acid (SUA), is a common form of arthritis that is induced by urate crystals. A single nucleotide polymorphism, rs2544390, of LDL receptor related protein 2 (LRP2/Megalin), has previously been reported to be associated with SUA by a genome-wide association study in a Japanese population. However, it was controversial as to whether rs2544390 is associated with gout in a...

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Identifiers

PMID: 31975031
DOI: 10.1007/s13577-019-00318-5
PMCID: PMC7080676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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