Genetic and epigenetic contribution of ABCG2 to gout susceptibility: a case-control study.

doi:10.1007/s11033-025-11380-8

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Article

Genetic and epigenetic contribution of ABCG2 to gout susceptibility: a case-control study.

Molecular biology reports - 29 Dec 2025

Clavijo-Cornejo Denise, Torres Javier Fernández, Santamaria-Olmedo Mónica, Zamudio-Cuevas Yessica, Martínez-Flores Karina, Flores-López Alba Paulina, López-Macay Ambar

Abstract excerpt

BACKGROUND: Gout is a disease characterized by joint pain due to an inflammatory response triggered by the precipitation of monosodium urate (MSU) crystals in joints. ATP-binding cassette subfamily G member 2 (ABCG2) is a protein involved in urate transport and in the protection of cells against drugs. OBJECTIVE: Analyze the effect of the presence of the ABCG2 single nucleotide polymorphisms (SNPs) rs2231142 and...

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PMID: 41460367
DOI: 10.1007/s11033-025-11380-8

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ABCG2
TG

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