Article
Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males: a case-control study.
BMC medical genetics - 20 Aug 2015
Zhou Zhao-Wei, Cui Ling-Ling, Han Lin, Wang Can, Song Zhi-Jian, Shen Jia-Wei, Li Zhi-Qiang, Chen Jian-Hua, Wen Zu-Jia, Wang Xiao-Min, Shi Yong-Yong, Li Chang-Gui
Abstract excerpt
BACKGROUND: Gout is a common arthritic disease resulting from elevated serum uric acid (SUA) level. A large meta-analysis including 28,141 individuals identified nine single nucleotide polymorphisms (SNPs) associated with altered SUA level in a Caucasian population. However, raised SUA level alone is not sufficient for the development of gout arthritis and most of these SNPs have not been studied in a Han Chinese...
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