Article
Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility.
Rheumatology international - 1 Apr 2014
Nakayama Akiyoshi, Matsuo Hirotaka, Shimizu Toru, Takada Yuzo, Nakamura Takahiro, Shimizu Seiko, Chiba Toshinori, Sakiyama Masayuki, Naito Mariko, Morita Emi, Ichida Kimiyoshi, Shinomiya Nariyoshi
Abstract excerpt
A recent genome-wide association study revealed that there is an association between serum uric acid (SUA) levels and rs2544390, a common variant in low-density lipoprotein-related protein 2 (LRP2/Megalin) gene. Two other variants of LRP2, rs2229268 and rs3755166, are also found to have associati...
Read the complete abstract on PubMed