Article
Lineage EM algorithm for inferring latent states from cellular lineage trees.
Bioinformatics (Oxford, England) - 1 May 2020
Nakashima So, Sughiyama Yuki, Kobayashi Tetsuya J
Abstract excerpt
SUMMARY: Phenotypic variability in a population of cells can work as the bet-hedging of the cells under an unpredictably changing environment, the typical example of which is the bacterial persistence. To understand the strategy to control such phenomena, it is indispensable to identify the phenotype of each cell and its inheritance. Although recent advancements in microfluidic technology offer us useful lineage...
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