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Article

Inferring epigenetic dynamics from kin correlations.

Proceedings of the National Academy of Sciences of the United States of America - 5 May 2015

Hormoz Sahand, Desprat Nicolas, Shraiman Boris I

Abstract excerpt

Populations of isogenic embryonic stem cells or clonal bacteria often exhibit extensive phenotypic heterogeneity that arises from intrinsic stochastic dynamics of cells. The phenotypic state of a cell can be transmitted epigenetically in cell division, leading to correlations in the states of cells related by descent. The extent of these correlations is determined by the rates of transitions between the...

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Identifiers

PMID: 25902540
DOI: 10.1073/pnas.1504407112
PMCID: PMC4426465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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