Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spatial and phenotypic characterization of pancreatic cancer-associated fibroblasts after neoadjuvant treatment.

Histology and histopathology - 1 Aug 2020

Nielsen Michael Friberg Bruun, Mortensen Michael Bau, Sørensen Mia Dahl, Wirenfeldt Martin, Kristensen Bjarne Winther, Schrøder Henrik Daa, Pfeiffer Per, Detlefsen Sönke

Abstract excerpt

Pancreatic ductal adenocarcinoma (PC) is characterized by a highly fibrotic desmoplastic stroma. Subtypes of cancer-associated fibroblasts (CAFs) have been identified in chemotherapy-naïve PC (CTN-PC), but their precise functions are still unclear. Our knowledge regarding the properties of CAFs in the regressive stroma after neoadjuvant treatment (NAT) of PC (NAT-PC) is particularly limited. We aimed to examine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-Associated Fibroblasts
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemotherapy, Adjuvant

Share to Fluorouracil

Share to Irinotecan

Share to Leucovorin

Share to Neoadjuvant Therapy

Share to Oxaliplatin

Source

Identifiers

PMID: 31960942
DOI: 10.14670/HH-18-201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spatial and phenotypic characterization of pancreatic cancer-associated fibroblasts after neoadjuvant treatment.PMID 31960942Read ↗

The Cellular Origins of Cancer-Associated Fibroblasts and Their Opposing Contributions to Pancreatic Cancer GrowthSemantic proximity Read ↗

A distinctive tumor compartment in pancreatic lobules defined by nascent stroma and classical tumor cell phenotypeSemantic proximity Read ↗

Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Three Distinct Stroma Types in Human Pancreatic Cancer Identified by Image Analysis of Fibroblast Subpopulations and CollagenSemantic proximity Read ↗

Pancreatic cancer stroma: controversies and current insightsSemantic proximity Read ↗

Effect of Stroma-directed Drugs in Combination with Chemotherapy Against Pancreatic Cancer- a Preclinical StudySemantic proximity Read ↗

Stromal biology of pancreatic cancerSemantic proximity Read ↗

Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes.Semantic proximity Read ↗

Adipose‐derived mesenchymal stem cells differentiate into pancreatic cancer‐associated fibroblasts in vitroSemantic proximity Read ↗

Longitudinal Analysis of Matched Patient Biospecimens Reveals Neural Reprogramming of Cancer-Associated Fibroblasts Following Chemotherapy in Pancreatic CancerSemantic proximity Read ↗

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.