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Pancreatic cancer stroma: controversies and current insights

24 Feb 2017

Abstract excerpt

Pancreatic cancer is characterized by a dense stromal response. The stroma includes a heterogeneous mass of cells, including pancreatic stellate cells, fibroblasts, immune cells and nerve cells, as well as extracellular matrix proteins, cytokines and growth factors, which interact with the tumor cells. Previous research has indicated that stromal elements contribute to tumor growth and aggressiveness. However,...

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PMID: 28276831
DOI: 10.1080/00365521.2017.1293726

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