Article
Frequent KRAS and HRAS mutations in squamous cell papillomas of the head and neck.
The journal of pathology. Clinical research - 1 Apr 2020
Sasaki Eiichi, Masago Katsuhiro, Fujita Shiro, Hanai Nobuhiro, Yatabe Yasushi
Abstract excerpt
Squamous cell papilloma (SCP) is a benign neoplasm of the head and neck. Human papillomavirus (HPV) has been reported to be a tumourigenic factor for SCP. However, not all SCPs are positive for HPV, suggesting that other possible mechanisms are involved in their development. In this study, we examined the mutational status of 51 SCPs using targeted panel sequencing in addition to HPV status using GP5+/GP6+ PCR....
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