Article
EGFR mutation and HPV infection in sinonasal inverted papilloma and squamous cell carcinoma.
Rhinology - 1 Aug 2020
Cabal V N, Menendez M, Vivanco B, Potes-Ares S, Riobello C, Suarez-Fernandez L, Garcia-Marin R, Blanco-Lorenzo V, Lopez F, Alvarez-Marcos C, Llorente J L, Hermsen M A
Abstract excerpt
BACKGROUND: To evaluate the involvement of EGFR signalling and HPV infection in a cohort of inverted sinonasal papilloma (ISP) and sinonasal squamous cell carcinoma (SNSCC) and their value for prognosis and clinical treatment. METHODS: We analysed 55 ISP, 14 SNSCC associated with ISP (SNSCC-isp) and and 60 SNSCC not associated with ISP (SNSCC-novo) for EGFR gene mutation and copy number gain, protein expression...
Topics
- Carcinoma, Squamous Cell
- ErbB Receptors
- Humans
- Mutation
- Papilloma, Inverted
- Papillomavirus Infections
