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Article

Sinonasal papillomas: A single centre experience on 137 cases with emphasis on malignant transformation and EGFR/KRAS status in "carcinoma ex papilloma".

Annals of diagnostic pathology - 1 Jun 2020

Maisch Saskia, Mueller Sarina K, Traxdorf Maximilian, Weyerer Veronika, Stoehr Robert, Iro Heinrich, Hartmann Arndt, Agaimy Abbas

Abstract excerpt

Among the three major histological subtypes of sinonasal papillomas, inverted (ISP) and oncocytic (OSP) sinonasal papillomas tend to undergo malignant transformation to carcinoma. However, criteria determining risk of recurrence and malignant progression have not been established. Recently, EGFR and KRAS mutations were detected to be characteristic for ISP and OSP, respectively. In this study, we analyzed 137...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma
Cell Transformation, Neoplastic
ErbB Receptors
Female
Humans
Male
Middle Aged
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nose Neoplasms

Papilloma

Paranasal Sinus Neoplasms

Proto-Oncogene Proteins p21(ras)

Young Adult

Source

Identifiers

PMID: 32203683
DOI: 10.1016/j.anndiagpath.2020.151504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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