Article
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
Nature communications - 16 Jan 2020
Linker K E, Gad M, Tawadrous P, Cano M, Green K N, Wood M A, Leslie F M
Abstract excerpt
With the rise of e-cigarette use, teen nicotine exposure is becoming more widespread. Findings from clinical and preclinical studies show that the adolescent brain is particularly sensitive to nicotine. Animal studies have demonstrated that adolescent nicotine exposure increases reinforcement for cocaine and other drugs. However, the mechanisms that underlie these behaviors are poorly understood. Here, we report...
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