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Article

cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel.

Genome biology - 17 Jan 2020

Frochaux Michael V, Bou Sleiman Maroun, Gardeux Vincent, Dainese Riccardo, Hollis Brian, Litovchenko Maria, Braman Virginie S, Andreani Tommaso, Osman Dani, Deplancke Bart

Abstract excerpt

BACKGROUND: Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but our understanding of how the effects of genetic variants affect different molecular mechanisms to determine gut immunocompetence is still limited. RESULTS: To address this,...

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Identifiers

PMID: 31948474
DOI: 10.1186/s13059-019-1912-z
PMCID: PMC6966807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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