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Article

The impact of species-wide gene expression variation on Caenorhabditis elegans complex traits.

Nature communications - 16 Jun 2022

Zhang Gaotian, Roberto Nicole M, Lee Daehan, Hahnel Steffen R, Andersen Erik C

Abstract excerpt

Phenotypic variation in organism-level traits has been studied in Caenorhabditis elegans wild strains, but the impacts of differences in gene expression and the underlying regulatory mechanisms are largely unknown. Here, we use natural variation in gene expression to connect genetic variants to differences in organismal-level traits, including drug and toxicant responses. We perform transcriptomic analyses on 207...

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Identifiers

PMID: 35710766
DOI: 10.1038/s41467-022-31208-4
PMCID: PMC9203580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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