Article
Genome-wide association studies identify new candidate genes and tissues underlying resistance to a natural toxin in drosophilids.
G3 (Bethesda, Md.) - 1 Apr 2026
Marconcini Michele, Fragnière Caroline, Masuzzo Ambra, Benton Richard
Abstract excerpt
Many insects can rapidly evolve resistance to artificial insecticides through changes in toxin target proteins. Over longer timescales, insects also evolve resistance to naturally occurring toxins to exploit new ecological niches, but the underlying mechanisms often remain poorly understood. A classic example is Drosophila sechellia, an extreme specialist for the ripe noni fruit of Morinda citrifolia. Noni is...
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