Pervasive tissue-, genetic background-, and allele-specific gene expression effects in Drosophila melanogaster.

doi:10.1371/journal.pgen.1011257

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Article

Pervasive tissue-, genetic background-, and allele-specific gene expression effects in Drosophila melanogaster.

PLoS genetics - 1 Aug 2024

Glaser-Schmitt Amanda, Lemoine Marion, Kaltenpoth Martin, Parsch John

Abstract excerpt

The pervasiveness of gene expression variation and its contribution to phenotypic variation and evolution is well known. This gene expression variation is context dependent, with differences in regulatory architecture often associated with intrinsic and environmental factors, and is modulated by regulatory elements that can act in cis (linked) or in trans (unlinked) relative to the genes they affect. So far,...

Topics

Animals
Drosophila melanogaster
Alleles
Genetic Background
Organ Specificity
Malpighian Tubules
Transcriptome
Genetic Variation
Gene Expression Regulation
Male
Female

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Identifiers

PMID: 39178312
DOI: 10.1371/journal.pgen.1011257
PMCID: PMC11376557

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