Article
Cryptic genetic variation of expression quantitative trait locus architecture revealed by genetic perturbation in Caenorhabditis elegans.
G3 (Bethesda, Md.) - 2 May 2023
van Wijk Marijke H, Riksen Joost A G, Elvin Mark, Poulin Gino B, Maulana Muhammad I, Kammenga Jan E, Snoek Basten L, Sterken Mark G
Abstract excerpt
Genetic perturbation in different genetic backgrounds can cause a range of phenotypes within a species. These phenotypic differences can be the result of the interaction between the genetic background and the perturbation. Previously, we reported that perturbation of gld-1, an important player in the developmental control of Caenorhabditis elegans, released cryptic genetic variation (CGV) affecting fitness in...
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