Article
Genotype and gene expression associations with immune function in Drosophila.
PLoS genetics - 1 Jan 2010
Sackton Timothy B, Lazzaro Brian P, Clark Andrew G
Abstract excerpt
It is now well established that natural populations of Drosophila melanogaster harbor substantial genetic variation associated with physiological measures of immune function. In no case, however, have intermediate measures of immune function, such as transcriptional activity of immune-related genes, been tested as mediators of phenotypic variation in immunity. In this study, we measured bacterial load sustained...
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