Article
Current and upcoming mitochondrial targets for cancer therapy.
Seminars in cancer biology - 1 Dec 2017
Kim Hyoung Kyu, Noh Yeon Hee, Nilius Bernd, Ko Kyung Soo, Rhee Byoung Doo, Kim Nari, Han Jin
Abstract excerpt
Mitochondria are essential intracellular organelles that regulate energy metabolism, cell death, and signaling pathways that are important for cell proliferation and differentiation. Therefore, mitochondria are fundamentally implicated in cancer biology, including initiation, growth, metastasis, relapse, and acquired drug resistance. Based on these implications, mitochondria have been proposed as a major...
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