Article
Comparison study for genotyping of a single-nucleotide polymorphism in the tumor necrosis factor promoter gene.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 2002
Juszczynski Przemysław, Woszczek Grzegorz, Borowiec Maciej, Kowalski Marek, Robak Tadeusz, Biliński Przemysław, Salles Gilles, Warzocha Krzysztof
Abstract excerpt
A variety of methods that address the detection of single-nucleotide polymorphism (SNP) have been used in molecular diagnostics. The allele-specific polymerase chain reaction (ASPCR) has been one of the most extensively studied, including its application in the tumor necrosis factor (TNF)(-308) genotyping. Many studies have demonstrated that the ASPCR sensitivity and specificity depends on various PCR parameters,...
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