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Article

Integrating DNA sequencing and transcriptomic data for association analyses of low-frequency variants and lipid traits.

Human molecular genetics - 1 Feb 2020

Yang Tianzhong, Wu Chong, Wei Peng, Pan Wei

Abstract excerpt

Transcriptome-wide association studies (TWAS) integrate genome-wide association studies (GWAS) and transcriptomic data to showcase their improved statistical power of identifying gene-trait associations while, importantly, offering further biological insights. TWAS have thus far focused on common variants as available from GWAS. Compared with common variants, the findings for or even applications to low-frequency...

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Identifiers

PMID: 31919517
DOI: 10.1093/hmg/ddz314
PMCID: PMC7015848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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