Article
Impact of miR-SNP rs2910164 on miR-146a expression in osteoarthritic chondrocytes.
Advances in medical sciences - 1 Mar 2020
Papathanasiou Ioanna, Mourmoura Evanthia, Balis Charalampos, Tsezou Aspasia
Abstract excerpt
PURPOSE: MiR-146a acts as a negative inflammatory mediator in different diseases and has been implicated in osteoarthritis (OA) pathogenesis. In our study, we investigated the association between miR-SNP rs2910164 and OA susceptibility and its role on the expression of miR-146a, inflammatory and catabolic mediators in osteoarthritic chondrocytes. MATERIALS AND METHODS: Genetic association analysis was performed...
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