Article
Association analysis of miRNA-146a and miRNA-499 polymorphisms with rheumatoid arthritis: a case-control and trio-family study.
Clinical and experimental medicine - 1 Sept 2023
Ul Islam Zia, Baneen Umul, Khaliq Taqdees, Nurulain Syed Muhammad, Muneer Zahid, Hussain Sabir
Abstract excerpt
Single nucleotide polymorphism is known to alter the expression and processing of miRNAs leading to a variety of diseases including rheumatoid arthritis (RA). However, disagreement is present up to date regarding the association of miRNA-146a and miRNA-499 polymorphisms with RA. The goal of this study was to assess the association of polymorphisms at miRNA-146a and miRNA-499 with the pathogenesis of RA in...
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