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Exploring the Associations and Molecular Impacts of miR-146a/rs2910164 and miR-196a2/rs185070757 with Rheumatoid Arthritis in a Pakistani Population.

Lifestyle genomics - 1 Jan 2023

Ali Yasir, Khan Aamir, Akhtar Mehran, Khan Suleman, Islam Zia Ul, Farooqi Nadia, Shah Aftab Ali, Chen Yangchao, Jalil Fazal

Abstract excerpt

INTRODUCTION: MicroRNAs (miRNAs) are a new class of molecules that participate in post-transcriptional regulation of gene expression and hence have been reported to have a crucial role in the pathogenesis of rheumatoid arthritis (RA). We aimed to investigate the association of miR-146a rs2910164 (G/C) and miR-196a2 rs185070757 (T/G) with RA susceptibility in Pakistani patients and to bioinformatically predict the...

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PMID: 37369185
DOI: 10.1159/000526937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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