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Article

Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death.

Cell calcium - 1 Mar 2020

Britti Elena, Ros Joaquim, Esteras Noemi, Abramov Andrey Y

Abstract excerpt

Aggregation or phosphorylation of the microtubule-associated protein tau is the pathological hallmark in a number of diseases termed tauopathies, which include the most common neurodegenerative disorder, Alzheimer's disease; or frontotemporal dementia, linked to mutations in the gene MAPT encoding tau. Although misfolded tau has strong familial and histopathological (as in intracellular tangles) association with...

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Identifiers

PMID: 31918031
DOI: 10.1016/j.ceca.2019.102150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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