Article
Life Course Adiposity and Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study.
Annals of neurology - 1 Mar 2020
Zhang Linjing, Tang Lu, Huang Tao, Fan Dongsheng
Abstract excerpt
OBJECTIVE: Observational studies have indicated that life course adiposity is associated with amyotrophic lateral sclerosis (ALS). However, whether such an association reflects causality remains unclear. We aimed to determine whether life course adiposity such as birth weight (BW), childhood body mass index (BMI), adult BMI, body fat percentage (BF%), and waist-to-hip ratio (WHR) have causal effects on ALS....
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