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Article

Mendelian randomization study supports relative carbohydrate intake as an independent risk factor for amyotrophic lateral sclerosis.

Nutritional neuroscience - 1 Jan 2025

Zeng Youjie, Guo Ren, Cao Si, Chavarria Gonzalez Sarel, Pang Ke, Liu Chunxia, Yang Heng

Abstract excerpt

OBJECTIVES: Observational studies suggested a potential correlation between dietary intake and amyotrophic lateral sclerosis (ALS), but conflicting findings exist and causality remains unclear. Here, we performed a Mendelian randomization (MR) analysis to evaluate the causal impact of relative intake of (i) carbohydrate, (ii) fat, and (iii) protein on ALS risk. METHODS: The genome-wide association summary...

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Source

Identifiers

PMID: 38781481
DOI: 10.1080/1028415X.2024.2352196

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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