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Article

Interaction between APOE4 and herpes simplex virus type 1 in Alzheimer's disease

1 Jan 2020

Abstract excerpt

INTRODUCTION: Numerous results suggest the implication of infectious agents in the onset of Alzheimer's disease (AD). METHODS: In the Bordeaux-3C prospective cohort, we assessed the impact of herpes simplex virus type 1 (HSV-1) infection on the incidence of AD according to apolipoprotein E (APOE) status, a genetic susceptibility factor. Cox models were performed to estimate the 10-year risk of AD associated with...

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PMID: 31914220
DOI: 10.1002/alz.12008

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