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Article

Herpes simplex virus type 1 in brain and risk of Alzheimer's disease.

Lancet (London, England) - 25 Jan 1997

Itzhaki R F, Lin W R, Shang D, Wilcock G K, Faragher B, Jamieson G A

Abstract excerpt

BACKGROUND: The apolipoprotein E epsilon 4 (APOE-epsilon 4) allele is a risk factor for Alzheimer's disease (AD), but it is neither essential nor sufficient for development of the disease. Other factors-genetic or environmental-must therefore have a role. By means of a PCR we have detected herpes simplex virus type 1 (HSV1) in latent form in brains of elderly people with and without AD. We have postulated that...

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Source

Identifiers

PMID: 9014911
DOI: 10.1016/S0140-6736(96)10149-5

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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