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Article

Circulating PACAP peptide and PAC1R genotype as possible transdiagnostic biomarkers for anxiety disorders in women: a preliminary study.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2020

Ross Rachel A, Hoeppner Susanne S, Hellberg Samantha N, O'Day Emily B, Rosencrans Peter L, Ressler Kerry J, May Víctor, Simon Naomi M

Abstract excerpt

Pituitary adenylate cyclase activating polypeptide (PACAP, gene Adcyap1) is a neuropeptide and hormone thought to play a critical role in stress response (Stroth et al., Ann NY Acad Sci 1220:49-59, 2011; Hashimoto et al., Curr Pharm Des 17:985-989, 2011). Research in humans implicates PACAP as a useful biomarker for the severity of psychiatric symptoms in response to psychological stressors, and work in rodent...

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PMID: 31910434
DOI: 10.1038/s41386-020-0604-4
PMCID: PMC7235237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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