Article
ADCYAP1R1 genotype associates with post-traumatic stress symptoms in highly traumatized African-American females.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2013
Almli Lynn M, Mercer Kristina B, Kerley Kimberly, Feng Hao, Bradley Bekh, Conneely Karen N, Ressler Kerry J
Abstract excerpt
Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptor (PAC1) play a critical role in biological processes that mediate stress response and have been implicated in psychological outcome following trauma. Our previous work [Ressler et al. (2011); Nature 470:492-497] demonstrated that a variant, rs2267735, in the gene encoding PAC1 (ADCYAP1R1) is associated with post-traumatic stress disorder...
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