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Article

Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2010

Unschuld Paul G, Ising Marcus, Roeske Darina, Erhardt Angelika, Specht Michael, Kloiber Stefan, Uhr Manfred, Müller-Myhsok Bertram, Holsboer Florian, Binder Elisabeth B

Abstract excerpt

Galanin (GAL) is an estrogen-inducible neuropeptide, highly expressed in brain regions reported to be involved in regulation of mood and anxiety. GAL possibly has a direct modulatory effect on hypothalamic-pituitary-adrenal (HPA)-axis regulation. Recent data from pharmacological and genetic studies indicate a significant function of GAL in stress-related disorders. By using a tag SNP approach covering the locus...

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Identifiers

PMID: 20237460
DOI: 10.1038/npp.2010.30
PMCID: PMC3055457

Genes

GAL
CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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