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Article

PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus.

Proceedings of the National Academy of Sciences of the United States of America - 25 Feb 2014

Stevens Jennifer Strafford, Almli Lynn M, Fani Negar, Gutman David A, Bradley Bekh, Norrholm Seth D, Reiser Emily, Ely Timothy D, Dhanani Rahim, Glover Ebony M, Jovanovic Tanja, Ressler Kerry J

Abstract excerpt

We have recently found higher circulating levels of pituitary adenylate cyclase-activating polypeptide (PACAP) associated with posttraumatic stress disorder (PTSD) symptoms in a highly traumatized cohort of women but not men. Furthermore, a single nucleotide polymorphism in the PACAP receptor gene ADCYAP1R1, adenylate cyclase activating polypeptide 1 receptor type 1, was associated with individual differences in...

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Identifiers

PMID: 24516127
DOI: 10.1073/pnas.1318954111
PMCID: PMC3939867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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