Article
Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 2 Feb 2018
Zhao Yan, He Awen, Zhu Feng, Ding Miao, Hao Jingcan, Fan Qianrui, Li Ping, Liu Li, Du Yanan, Liang Xiao, Guo Xiong, Zhang Feng, Ma Xiancang
Abstract excerpt
Schizophrenia is a serious mental disease with high heritability. To better understand the genetic basis of schizophrenia, we conducted a large scale integrative analysis of genome-wide association study (GWAS) and expression quantitative trait loci (eQTLs) data. GWAS summary data was derived from a published GWAS of schizophrenia, containing 9394 schizophrenia patients and 12,462 healthy controls. The eQTLs...
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