Article
Genetic variants in toll-like receptor 4 are associated with lack of steroid-responsiveness in pediatric ITP patients.
American journal of hematology - 1 Apr 2020
Kim Taylor Olmsted, Flanagan Jonathan M, Habibi Ali, Arulselvan Abinaya, Lambert Michele P, Grace Rachael F, Despotovic Jenny M
Abstract excerpt
Although the most common front-line therapies for immune thrombocytopenia (ITP) have been in use for decades, it is still not possible to predict an individual patient's clinical course and response to therapy. Patients are managed with a trial-and-error approach and often suffer side effects of therapies which could have been avoided if response prediction were possible. Corticosteroids are the most frequently...
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