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Article

Toll-Like Receptor 9 (TLR9) Gene C/T (rs352140) Polymorphisms in Adult Primary Immune Thrombocytopenia.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jan 2000

Hassan Alaa Efat, Shoeib Sabry, Abdelmohsen Esaam, Nazir Aida, Dawood Ashraf, Gamal Heba, Abdelhafez Mohamed

Abstract excerpt

Immune thrombocytopenia (ITP) is an autoimmune disease characterized by low platelet count and increased bleeding risk. The initial event(s) leading to antiplatelet autoimmunity remains unclear. Toll-like receptors (TLRs) are the most well-characterized pattern recognition receptors and are a transmembrane protein coded by the Toll genes family. In addition to their protective role in immunity, it is also...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32729323
DOI: 10.1177/1076029620940050
PMCID: PMC7394025

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