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Article

Frequency of toll-like receptor 4 variants and association with treatment response in children with primary immune thrombocytopenia.

Pediatric blood & cancer - 1 Nov 2023

Ahmed Heba A, Fahmy Eman M, Abdelkreem Elsayed, Mahmoud Ekram A, Nafady Asmaa, Ahmed Eman H

Abstract excerpt

OBJECTIVES: To investigate the frequency of toll-like receptor 4 (TLR4) variants c.896A>G (p.Asp299Gly) and c.1196C>T (p.Thr399Ile) among Egyptian children with primary immune thrombocytopenia (pITP), and their association with disease course and response to treatment. METHODS: A case-control study that included 80 children with pITP and 50 age- and sex-matched healthy controls. TLR4 c.896A>G and c.1196C>T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37638833
DOI: 10.1002/pbc.30646

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