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Article

Enhanced oligomerization of full-length RAGE by synergy of the interaction of its domains.

Scientific reports - 30 Dec 2019

Moysa Alexander, Hammerschmid Dietmar, Szczepanowski Roman H, Sobott Frank, Dadlez Michal

Abstract excerpt

The pattern recognition receptor RAGE (receptor for advanced glycation end-products) transmits proinflammatory signals in several inflammation-related pathological states, including vascular diseases, cancer, neurodegeneration and diabetes. Its oligomerization is believed to be important in signal transduction, but RAGE oligomeric structures and stoichiometries remain unclear. Different oligomerization modes have...

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Identifiers

PMID: 31889156
DOI: 10.1038/s41598-019-56993-9
PMCID: PMC6937306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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