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Article

Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex.

Acta crystallographica. Section D, Biological crystallography - 1 May 2015

Jensen Jaime L, Indurthi Venkata S K, Neau David B, Vetter Stefan W, Colbert Christopher L

Abstract excerpt

S100B is a damage-associated molecular pattern protein that, when released into the extracellular milieu, triggers initiation of the inflammatory response through the receptor for advanced glycation end products (RAGE). Recognition of S100B is accomplished via the amino-terminal variable immunoglobulin domain (V-domain) of RAGE. To gain insights into this interaction, a complex between S100B and a 15-amino-acid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25945582
DOI: 10.1107/S1399004715004216
PMCID: PMC4427201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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