Article
Identification, classification, and expression of RAGE gene splice variants.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2008
Hudson Barry I, Carter Angela M, Harja Evis, Kalea Anastasia Z, Arriero Maria, Yang Hojin, Grant Peter J, Schmidt Ann Marie
Abstract excerpt
The receptor for advanced glycation end-products (RAGE) is a single-transmembrane, multiligand receptor of the immunoglobulin superfamily. RAGE up-regulation is implicated in numerous pathological states including vascular disease, diabetes, cancer, and neurodegeneration. The understanding of the regulation of RAGE is important in both disease pathogenesis and normal homeostasis. Here, we demonstrate the...
Topics
- Alternative Splicing
- Base Sequence
- Cells, Cultured
- Cloning, Molecular
- Computational Biology
- Genetic Variation
- Humans
- Lung
- Molecular Sequence Data
- Muscle, Smooth, Vascular
- Protein Structure, Tertiary
- Receptor for Advanced Glycation End Products